I can play more in next days with that game and will see what I can do. In rare situation is possible make fix for that, but it’s very rare. For example settlr1 means settlers 1, synd means syndicate, ms mouse means win3.1/95.
But why don’t you play with relative mouse, it’s adventure, this is very well playable with relative mouse. From quick gameplay I tried relative mouse + two point tap gesture set to right click, in addition I set mouse sensitivity to 60 and it worked well.